Intracellular cAMP plays a crucial role in various neuronal functions such as ion channel activity, transcription, and synaptic plasticity, with cAMP-dependent protein kinases being essential for long-term potentiation (LTP) in the hippocampus. The study highlights that Ca2+-stimulated adenylyl cyclase, particularly type I adenylyl cyclase (I-AC), is significantly upregulated during the first two weeks of brain development in rats, contributing to neuroplasticity in regions like the hippocampus. 

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